Friday 4 April 2003
Organizer F. Silvestris (Bari, Italy)

Apoptosis in clinical medicine

Session I The altered apoptosis as disease mechanism(s)
Chairs F. Dammacco (Bari, Italy) & F. Indiveri (Genova, Italy) Abstract No.
09.40 – 09.45 Introduction
F. Dammacco (Bari, Italy)
09.45 – 10.10 Apoptosis: effector mechanisms and their derangements
G. Kroemer (Paris, France)
10.10 – 10.30 Physiological and pathological mechanisms of red cell production
R. De Maria (Rome, Italy)
10.30 – 10.50 Abnormal plasma cell apoptosis and tumor progression in multiple myeloma
F. Silvestris (Bari, Italy)
10.50 – 11.00 Discussion
11.00 – 11.15 coffee break
Session II Molecular mechanisms of apoptosis derangements and clinical diseases
Chairs G. Ricevuti (Pavia, Italy) & F. Silvestris (Bari, Italy) Abstract No.
11.15 – 11.35 Apoptosis induction by soluble HLA molecules in CD8+ T lymphocytes and natural killer cells
F. Puppo (Genova, Italy)
11.35 – 11.55 Secretion of pro-apoptotic intron-4-retaining soluble HLA-G1 by human villous trophoblast
P. Le Bouteiller (Toulouse, Paris)
11.55 – 12.00 Discussion
12.00 – 12.15 Reduced post-infarction myocardial apoptosis in women: a clue to their different clinical course?
G.G.L. Biondi-Zoccai, A. Abbate, R. Bussani, D. Camilot, Q. Parisi, A. Dobrina, and A. Baldi (Rome, Italy/Trieste, Italy/Naples, Italy)
12.15 – 12.30 Serum markers of apoptosis in dialysis patients
G. Sypniewska, A. Stefanska, and J. Manitius (Bydgoszcz, Poland)
12.30 – 12.45 Bcl-2 regulation by targeting the RNA adenine-uridine rich element
A. Bevilacqua, and A. Nicolin (Milan, Italy)
12.45 – 13.00 DNAse I behaves as a transcription factor which modulates FAS expression in human cells
M. Oliveri, A. Daga, C. Lunardi, R. Millo, R. Navone, C. Bason and A. Puccetti (Genova/Verona, Italy)
13.00 End of workshop


FAS in Sepsis and organ failure in a rat model
U. Glatzel, R. Tolba, M. Tinelli, M. Lysson, A. Wentzensen, and T. Minor (Ludwigshafen/Bonn, Germany)

High-risk clinical features predict increased post-infarction myocardial apoptosis and the benefits due to an open infarct-related artery
A. Abbate, G.G.L. Biondi-Zoccai, R. Bussani, D. Camilot, A.M. Leone, Q. Parisi, F. Silvestri, A. Dobrina, and A. Baldi (Rome/Trieste/Naples, Italy)

T cell activation and enhanced apoptosis in non-ST elevation myocardial infarction patients
A.L. Pasqui, M. Di Renzo, G. Bova, F. Bruni, L. Puccetti, M. Pastorelli, G. Pompella, and A. Auteri (Siena, Italy)