Friday, 16 April 2004
Organisers P. Portincasa (Bari, Italy)
K.J. van Erpecum (Utrecht, The Netherlands)

Biliary lipids and water:
novel aspects in secretion and therapeutic implication

Friday Morning
Chairs G.P. van Berge Henegouwen (Utrecht, The Netherlands) Abstract number
08.30 – 08.35 Introduction
P. Portincasa (Bari, Italy)
08.35 – 09.00 Novel aspects of biliary secretion
R. Oude Elferink (Amsterdam, The Netherlands)
09.00 – 09.30 Aquaporins and bile secretion in the hepatobiliary tract
G. Calamita (Bari, Italy)
09.30 – 09.45 The gallbladder: lipid and water handling
P. Portincasa (Bari, Italy)
09.45 – 10.00 Effects of lithogenic diet on murine gallbladder histology: implications for gallbladder concentrating function, motility and aquaporin expression
K.J. van Erpecum (Utrecht, The Netherlands)
10.00 – 11.15 coffee break + plenary lecture
11.30 – 12.00 Relevance of Lith genes for human gallstone formation
F. Lammert (Aachen, Germany)
99 / 100
12.00 – 12.30 Molecular dynamics simulations: bile salts, vesicles and cholesterol crystallization
S.J. Marrink (Groningen, The Netherlands)
12.30 – 13.00 poster presentations
13.00 end of workshop
Gallbladder bile proteins in different types of gallstone patients. Relation to stone composition, protein oxidation and cholesterol crystallization time
P. Portincasa, I. Grattagliano, A. Moschetta, A. Di Ciaula, and G. Palasciano (Bari, Italy)
Increased micellar phospholipids are needed to prevent bile salt (BS)-detergent activity in presence of bilirubin (BI): relevance in cholestasis
P. Portincasa, A. Moschetta, M. Petruzzelli, M. Vacca, M. Krawczyk, and G. Palasciano (Bari, Italy; Lublin, Poland)
Time-dependent changes in bile secretion and composition after orthotopic liver transplantation (OLT): a simple tool to predict a positive outcome
P. Portincasa, A. Moschetta, G. Lupo, M.T. Rotelli, M. Petruzzelli, R. De Venuto, A. Panebianco, P.C. Panzera, G. Carbotta, I. Grattagliano, V. Memeo, and G. Palasciano
(Bari, Italy)
Possible functional involvement of AQP1, AQP8 and AQP9 in bile formation and bile flow in the hepatobiliary tract
G. Calamita, D. Ferri, A. Mazzone, P. Gena, P. Roberti, G. Cassano, P. Portincasa, G. E. Liquori, and M. Svelto (Bari, Italy)
Ontogeny, localization and possible functional implications of the aquaporin-8 water channel (AQP8) in mouse liver
D. Ferri, A. Mazzone, G. E. Liquori, G. Cassano, M. Mastrodonato, M. Svelto, and G. Calamita (Bari, Italy)
Effects of hydrophobic and hydrophilic bile salts on gallstone growth and dissolution in model biles
K.J. van Erpecum, N.G. Venneman, M. van Kammen, and G.P. van Berge-Henegouwen (Utrecht, The Netherlands)