HDL metabolism

Thursday, 11 April 2002


R.P.F. Dullaart (Groningen, The Netherlands)
A. van Tol (Rotterdam. The Netherlands)

HDL function, reverse cholesterol transport and lipid transfer

Session I

Abstract no
Chairs A. van Tol (Rotterdam, The Netherlands)
R.P.F. Dullaart (Groningen, The Netherlands)
9.45 Welcome: R.P.F. Dullaart (Groningen, The Netherlands)  
9.45 – 10.15 Relevance of HDL subfractions for cardiovascular risk
M.R. Taskinen (Helsinki, Finland)
10.15 – 10.45 Regulation of apolipoprotein A1 synthesis
B. Staels (Lille, France)
10.45 – 11.15 coffee break  
11.15 – 11.30 Phospholipid transfer protein (PLTP) increases VLDL secretion in transgenic mice
J. Lie, T. van Gent, R. van Haperen, L. Scheek, I. Lankhuizen, R. de Crom, and A. van Tol (Rottrdam, The Netherlands)
11.30 – 11.45 Enhanced efflux of cholesterol from ABCA1-expressing J774 macrophages to serum from type IV hypertriglyceridemic subjects
N. Fournier , O. Francone, G. Rothblat, D. Goudouneche, L. Royer, N. Moatti , and J.L. Paul (Châtenay-Malabry, France / Groton, USA / Philadelphia, USA)
11.45 – 12.00 ATP-binding cassette transporter A1-mediated efflux of lipids from rodent type II lung cells
E. Favari, A. E. Bortnick, O. L. Francone, G. H. Rothblat, and S. R. Bates (Parma, Italy / Philadelphia, USA / Groton, USA)
12.00 – 12.15 Low paraoxanase activity as a risk factor for coronary heart disease
B. Mackness, P. Durrington, N. Azam, P. McElduff, and M . Mackness (Manchester UK)
12.15 – 12.30 discussion, end of session I  
12.30 – 14.00 lunch and poster viewing  

Session II

Chairs R.P.F. Dullaart (Groningen, The Netherlands)
A. van Tol (Rotterdam, The Netherlands)
15.00 – 15.30 Function of phospholipid transfer protein: studies in transgenic mice
R. de Crom (Rotterdam, The Netherlands)
15.30 – 16.00 Cell models for measuring cholesterol efflux
G.H. Rothblat (Philadelphia, USA)
16.00 – 16.30 ABC-1 gene and HDL deficiency
J.P. Kastelein (Amsterdam, The Netherlands)
16.30 – 16.45 Enhanced cellular cholesterol efflux and CE transfer from HDL to chylomicrons and VLDL-1 during postprandial lipemia in type IIB hyperlipidemia
M. Guerin, P. Egger, C. Soudant, W. le Goff, A. van Tol, R. Dupuis and M.J. Chapman (Paris, France / Rotterdam, The Netherlands)
16.45 – 17.00 Dose-dependent reduction of CETP mass after atorvastatin therapy in type 2 diabetes mellitus. The role of Taq1B and A-629C polymorphisms
F.V. van Venrooij, R.P. Stolk, J.D. Banga, T.P. Sijmonsma, D.W. Erkelens, and G.M. Dallinga-Thie, on behalf of the DALI study group (Utrecht, The Netherlands)
17.00 discussion and closure
A. van Tol (Rotterdam, The Netherlands)
17.00 end of workshop 8